| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RelA | SEL98454.1 | SAMN05444853_12231 | SAMN05444853_102148 | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ribonucleoside-triphosphate reductase. | 0.900 |
| RelA | SEM10750.1 | SAMN05444853_12231 | SAMN05444853_10547 | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | ATP diphosphatase. | 0.914 |
| RelA | SEM50733.1 | SAMN05444853_12231 | SAMN05444853_12110 | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Cyclic pyranopterin phosphate synthase; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | 0.801 |
| RelA | SEM64704.1 | SAMN05444853_12231 | SAMN05444853_1358 | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Adenylate cyclase, class 1. | 0.900 |
| RelA | folE | SAMN05444853_12231 | SAMN05444853_1385 | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | GTP cyclohydrolase I. | 0.800 |
| RelA | ndk | SAMN05444853_12231 | SAMN05444853_11844 | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.908 |
| SEL98454.1 | RelA | SAMN05444853_102148 | SAMN05444853_12231 | Ribonucleoside-triphosphate reductase. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.900 |
| SEL98454.1 | SEL98485.1 | SAMN05444853_102148 | SAMN05444853_102149 | Ribonucleoside-triphosphate reductase. | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.996 |
| SEL98454.1 | SEM06587.1 | SAMN05444853_102148 | SAMN05444853_10455 | Ribonucleoside-triphosphate reductase. | dGTPase; Belongs to the dGTPase family. Type 2 subfamily. | 0.900 |
| SEL98454.1 | SEM10750.1 | SAMN05444853_102148 | SAMN05444853_10547 | Ribonucleoside-triphosphate reductase. | ATP diphosphatase. | 0.907 |
| SEL98454.1 | SEM50733.1 | SAMN05444853_102148 | SAMN05444853_12110 | Ribonucleoside-triphosphate reductase. | Cyclic pyranopterin phosphate synthase; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | 0.800 |
| SEL98454.1 | SEM64704.1 | SAMN05444853_102148 | SAMN05444853_1358 | Ribonucleoside-triphosphate reductase. | Adenylate cyclase, class 1. | 0.916 |
| SEL98454.1 | dut | SAMN05444853_102148 | SAMN05444853_10956 | Ribonucleoside-triphosphate reductase. | dUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.910 |
| SEL98454.1 | folE | SAMN05444853_102148 | SAMN05444853_1385 | Ribonucleoside-triphosphate reductase. | GTP cyclohydrolase I. | 0.800 |
| SEL98454.1 | ndk | SAMN05444853_102148 | SAMN05444853_11844 | Ribonucleoside-triphosphate reductase. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.900 |
| SEL98454.1 | pyrG | SAMN05444853_102148 | SAMN05444853_11243 | Ribonucleoside-triphosphate reductase. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.903 |
| SEL98485.1 | SEL98454.1 | SAMN05444853_102149 | SAMN05444853_102148 | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | Ribonucleoside-triphosphate reductase. | 0.996 |
| SEM06587.1 | SEL98454.1 | SAMN05444853_10455 | SAMN05444853_102148 | dGTPase; Belongs to the dGTPase family. Type 2 subfamily. | Ribonucleoside-triphosphate reductase. | 0.900 |
| SEM06587.1 | ndk | SAMN05444853_10455 | SAMN05444853_11844 | dGTPase; Belongs to the dGTPase family. Type 2 subfamily. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.902 |
| SEM10750.1 | RelA | SAMN05444853_10547 | SAMN05444853_12231 | ATP diphosphatase. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.914 |
