| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SEL97039.1 | SEL97067.1 | SAMN05444853_10298 | SAMN05444853_10299 | Ribose transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. | Ribose transport system substrate-binding protein. | 0.893 |
| SEL97039.1 | fucA | SAMN05444853_10298 | SAMN05444853_10296 | Ribose transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. | L-fuculose-phosphate aldolase; Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. | 0.692 |
| SEL97039.1 | fucK | SAMN05444853_10298 | SAMN05444853_10294 | Ribose transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. | L-fuculokinase; Catalyzes the phosphorylation of L-fuculose. Belongs to the FGGY kinase family. | 0.493 |
| SEL97039.1 | fucU | SAMN05444853_10298 | SAMN05444853_10295 | Ribose transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. | L-fucose mutarotase; Involved in the anomeric conversion of L-fucose. | 0.645 |
| SEL97039.1 | rbsA | SAMN05444853_10298 | SAMN05444853_10297 | Ribose transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. | Ribose transport system ATP-binding protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. | 0.958 |
| SEL97067.1 | SEL97039.1 | SAMN05444853_10299 | SAMN05444853_10298 | Ribose transport system substrate-binding protein. | Ribose transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. | 0.893 |
| SEL97067.1 | fucA | SAMN05444853_10299 | SAMN05444853_10296 | Ribose transport system substrate-binding protein. | L-fuculose-phosphate aldolase; Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. | 0.492 |
| SEL97067.1 | fucU | SAMN05444853_10299 | SAMN05444853_10295 | Ribose transport system substrate-binding protein. | L-fucose mutarotase; Involved in the anomeric conversion of L-fucose. | 0.831 |
| SEL97067.1 | rbsA | SAMN05444853_10299 | SAMN05444853_10297 | Ribose transport system substrate-binding protein. | Ribose transport system ATP-binding protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. | 0.780 |
| asd | fucA | SAMN05444853_1077 | SAMN05444853_10296 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | L-fuculose-phosphate aldolase; Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. | 0.558 |
| asd | glyA | SAMN05444853_1077 | SAMN05444853_1381 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.618 |
| asd | metG | SAMN05444853_1077 | SAMN05444853_10860 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.490 |
| asd | metJ | SAMN05444853_1077 | SAMN05444853_1122 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | MetJ family transcriptional regulator, methionine regulon repressor; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.487 |
| asd | mtnN | SAMN05444853_1077 | SAMN05444853_10972 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | 0.487 |
| fucA | SEL97039.1 | SAMN05444853_10296 | SAMN05444853_10298 | L-fuculose-phosphate aldolase; Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. | Ribose transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. | 0.692 |
| fucA | SEL97067.1 | SAMN05444853_10296 | SAMN05444853_10299 | L-fuculose-phosphate aldolase; Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. | Ribose transport system substrate-binding protein. | 0.492 |
| fucA | asd | SAMN05444853_10296 | SAMN05444853_1077 | L-fuculose-phosphate aldolase; Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.558 |
| fucA | fucK | SAMN05444853_10296 | SAMN05444853_10294 | L-fuculose-phosphate aldolase; Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. | L-fuculokinase; Catalyzes the phosphorylation of L-fuculose. Belongs to the FGGY kinase family. | 0.844 |
| fucA | fucU | SAMN05444853_10296 | SAMN05444853_10295 | L-fuculose-phosphate aldolase; Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. | L-fucose mutarotase; Involved in the anomeric conversion of L-fucose. | 0.800 |
| fucA | glyA | SAMN05444853_10296 | SAMN05444853_1381 | L-fuculose-phosphate aldolase; Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.593 |