Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SEM00478.1Conserved protein HemX. (536 aa)    
Predicted Functional Partners:
SEM00509.1
HemY protein.
 
  
 0.976
SEM14317.1
DNA polymerase III, delta subunit.
  
     0.667
SEL91769.1
SH3 domain protein.
  
     0.541
SEM54858.1
Modulator of FtsH protease; Belongs to the BI1 family.
  
     0.539
dsbB
Disulfide bond formation protein DsbB; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.
 
     0.528
SEM02279.1
Hypothetical protein.
  
     0.513
lolA
Outer membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
  
     0.486
SEM00875.1
Hypothetical protein.
  
     0.482
SEM11250.1
Universal stress protein A; Required for resistance to DNA-damaging agents. Belongs to the universal stress protein A family.
  
     0.482
SEM64704.1
Adenylate cyclase, class 1.
 
    0.473
Your Current Organism:
Pasteurella skyensis
NCBI taxonomy Id: 97481
Other names: DSM 24204, NCIMB 13593, NCTC 13204, P. skyensis, Pasteurella skyensis Birkbeck et al. 2002, strain 95A1
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