| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SEM23755.1 | rpoA | SAMN05444853_10959 | SAMN05444853_102146 | CRP/FNR family transcriptional regulator, cyclic AMP receptor protein. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.929 |
| SEM23755.1 | rpoB | SAMN05444853_10959 | SAMN05444853_10238 | CRP/FNR family transcriptional regulator, cyclic AMP receptor protein. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.888 |
| SEM23755.1 | rpoC | SAMN05444853_10959 | SAMN05444853_10239 | CRP/FNR family transcriptional regulator, cyclic AMP receptor protein. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.888 |
| SEM23755.1 | rpoD | SAMN05444853_10959 | SAMN05444853_103146 | CRP/FNR family transcriptional regulator, cyclic AMP receptor protein. | RNA polymerase primary sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.938 |
| SEM23755.1 | rpoZ | SAMN05444853_10959 | SAMN05444853_1023 | CRP/FNR family transcriptional regulator, cyclic AMP receptor protein. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.880 |
| SspA | rpoA | SAMN05444853_101143 | SAMN05444853_102146 | RNA polymerase-associated protein; Belongs to the GST superfamily. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.908 |
| SspA | rpoB | SAMN05444853_101143 | SAMN05444853_10238 | RNA polymerase-associated protein; Belongs to the GST superfamily. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.906 |
| SspA | rpoC | SAMN05444853_101143 | SAMN05444853_10239 | RNA polymerase-associated protein; Belongs to the GST superfamily. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.925 |
| SspA | rpoD | SAMN05444853_101143 | SAMN05444853_103146 | RNA polymerase-associated protein; Belongs to the GST superfamily. | RNA polymerase primary sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.925 |
| SspA | rpoZ | SAMN05444853_101143 | SAMN05444853_1023 | RNA polymerase-associated protein; Belongs to the GST superfamily. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.927 |
| atpD | gyrA | SAMN05444853_102103 | SAMN05444853_10450 | ATP synthase F1 subcomplex beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.603 |
| atpD | rpoA | SAMN05444853_102103 | SAMN05444853_102146 | ATP synthase F1 subcomplex beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.868 |
| atpD | rpoB | SAMN05444853_102103 | SAMN05444853_10238 | ATP synthase F1 subcomplex beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.942 |
| atpD | rpoC | SAMN05444853_102103 | SAMN05444853_10239 | ATP synthase F1 subcomplex beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.765 |
| atpD | rpoD | SAMN05444853_102103 | SAMN05444853_103146 | ATP synthase F1 subcomplex beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. | RNA polymerase primary sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.806 |
| dnaG | gyrA | SAMN05444853_103145 | SAMN05444853_10450 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.470 |
| dnaG | nusA | SAMN05444853_103145 | SAMN05444853_10558 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | N utilization substance protein A; Participates in both transcription termination and antitermination. | 0.492 |
| dnaG | rpoA | SAMN05444853_103145 | SAMN05444853_102146 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.506 |
| dnaG | rpoB | SAMN05444853_103145 | SAMN05444853_10238 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.529 |
| dnaG | rpoD | SAMN05444853_103145 | SAMN05444853_103146 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | RNA polymerase primary sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.890 |
