Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SEM00601.1Hypothetical protein. (292 aa)    
Predicted Functional Partners:
argR
Transcriptional regulator of arginine metabolism; Regulates arginine biosynthesis genes.
       0.835
SEM42570.1
Ribosome-associated inhibitor A.
   
    0.647
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
       0.565
parC
Topoisomerase-4 subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
    0.505
lolB
Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
   
    0.456
SEM00647.1
tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase.
 
    0.451
SEM16445.1
Signal peptidase I; Belongs to the peptidase S26 family.
   
    0.429
SEM00531.1
Putative thioredoxin.
  
    0.402
Your Current Organism:
Pasteurella skyensis
NCBI taxonomy Id: 97481
Other names: DSM 24204, NCIMB 13593, NCTC 13204, P. skyensis, Pasteurella skyensis Birkbeck et al. 2002, strain 95A1
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