Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SEM01873.1PTS system, glucose-specific IIA component. (166 aa)    
Predicted Functional Partners:
SEM10099.1
PTS system, glucose-specific IIC component.
 0.999
SEM54207.1
PTS system, arbutin-like IIC component.
 0.999
SEM01896.1
Phosphotransferase system, enzyme I, PtsI; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.998
SEM01916.1
Phosphocarrier protein HPr.
 
 0.997
SEM07593.1
PTS system, sucrose-specific IIC component.
 
 0.987
SEM26729.1
PTS hybrid protein.
 
 
 0.979
SEM36535.1
PTS system, N-acetylglucosamine-specific IIC component.
 
 
 0.948
SEM22620.1
N-acetylglucosamine-6-phosphate deacetylase.
 
  
 0.929
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.922
murQ
N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
    
 0.912
Your Current Organism:
Pasteurella skyensis
NCBI taxonomy Id: 97481
Other names: DSM 24204, NCIMB 13593, NCTC 13204, P. skyensis, Pasteurella skyensis Birkbeck et al. 2002, strain 95A1
Server load: low (14%) [HD]