Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SEM02161.1MarR family transcriptional regulator, negative regulator of the multidrug operon emrRAB. (176 aa)    
Predicted Functional Partners:
EmrB
MFS transporter, DHA2 family, multidrug resistance protein; Belongs to the major facilitator superfamily.
 
   
 0.841
SEM02137.1
Membrane fusion protein, multidrug efflux system.
 
  
 0.813
SEM61531.1
Cell division protein FtsN.
  
    0.730
SEM30006.1
Chaperone TorD involved in molybdoenzyme TorA maturation.
  
    0.551
SEM20151.1
Two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB.
  
  
 0.539
mukF
Bacterial condensin subunit MukF; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
  
     0.519
SEM31047.1
Uncharacterized membrane protein YhdT.
  
     0.486
parC
Topoisomerase-4 subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
  
 0.455
glnS
glutaminyl-tRNA synthetase.
   
    0.450
matP
Hypothetical protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
  
     0.449
Your Current Organism:
Pasteurella skyensis
NCBI taxonomy Id: 97481
Other names: DSM 24204, NCIMB 13593, NCTC 13204, P. skyensis, Pasteurella skyensis Birkbeck et al. 2002, strain 95A1
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