Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SEM07698.1tRNA 2-thiouridine synthesizing protein D. (127 aa)    
Predicted Functional Partners:
SEM07721.1
tRNA 2-thiouridine synthesizing protein C; Belongs to the DsrF/TusC family.
 
 0.999
SEM07738.1
tRNA 2-thiouridine synthesizing protein B.
  
 
 0.993
SEM54888.1
tRNA 2-thiouridine synthesizing protein E; Part of a sulfur-relay system.
 
 
 0.989
tusA
tRNA 2-thiouridine synthesizing protein A; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family.
 
 
 0.981
SEM07677.1
Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains.
  
  
 0.854
SEM07650.1
FKBP-type peptidyl-prolyl cis-trans isomerase FkpA.
       0.661
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
 
  
 0.589
slyX
SlyX protein; Belongs to the SlyX family.
     
 0.482
sprT
SprT protein; Belongs to the SprT family.
  
     0.439
mnmA
tRNA-specific 2-thiouridylase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
     
 0.429
Your Current Organism:
Pasteurella skyensis
NCBI taxonomy Id: 97481
Other names: DSM 24204, NCIMB 13593, NCTC 13204, P. skyensis, Pasteurella skyensis Birkbeck et al. 2002, strain 95A1
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