Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
zapBCell division protein ZapB; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. (72 aa)    
Predicted Functional Partners:
SEM35040.1
Negative regulator of replication initiation SeqA; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated; Belongs to the SeqA family.
  
   
 0.791
SEM35662.1
Hypothetical protein; Belongs to the UPF0352 family.
  
   
 0.778
SEL96620.1
Hypothetical protein.
  
    0.769
lapA
Putative membrane protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.
  
     0.767
SEM65043.1
Acetolactate synthase, small subunit.
  
    0.766
SEM06487.1
DeoR family transcriptional regulator, glycerol-3-phosphate regulon repressor.
  
     0.758
SEM61309.1
Hypothetical protein.
  
     0.758
SEM56064.1
Conserved hypothetical protein.
  
     0.735
SEM07539.1
Hypothetical protein; Belongs to the UPF0263 family.
  
     0.709
SEM47098.1
Hypothetical protein.
  
     0.705
Your Current Organism:
Pasteurella skyensis
NCBI taxonomy Id: 97481
Other names: DSM 24204, NCIMB 13593, NCTC 13204, P. skyensis, Pasteurella skyensis Birkbeck et al. 2002, strain 95A1
Server load: low (14%) [HD]