STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEM14567.1Betaine-aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. (487 aa)    
Predicted Functional Partners:
SEM14541.1
Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
 
 0.983
betI
TetR/AcrR family transcriptional regulator, transcriptional repressor of bet genes; Repressor involved in choline regulation of the bet genes.
  
 0.940
SEM22837.1
Betaine-homocysteine S-methyltransferase.
   
 0.914
msrA
Peptide methionine sulfoxide reductase msrA/msrB; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 
 0.565
SEM01725.1
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
  
  
 0.492
SEM14493.1
Betaine/carnitine transporter, BCCT family; Belongs to the BCCT transporter (TC 2.A.15) family.
  
  
 0.489
SEM14514.1
Arsenate reductase.
  
    0.486
SEM60123.1
FAD/FMN-containing dehydrogenase.
  
  
 0.467
SEL94588.1
Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
 
 
0.457
SEL97096.1
Lactaldehyde reductase.
 
 
 0.457
Your Current Organism:
Pasteurella skyensis
NCBI taxonomy Id: 97481
Other names: DSM 24204, NCIMB 13593, NCTC 13204, P. skyensis, Pasteurella skyensis Birkbeck et al. 2002, strain 95A1
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