| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SEM14612.1 | SEM14634.1 | SAMN05444853_10658 | SAMN05444853_10659 | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Hypothetical protein; Belongs to the UPF0250 family. | 0.568 |
| SEM14612.1 | SEM54732.1 | SAMN05444853_10658 | SAMN05444853_12329 | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.921 |
| SEM14612.1 | lipA | SAMN05444853_10658 | SAMN05444853_10661 | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.514 |
| SEM14612.1 | lipB | SAMN05444853_10658 | SAMN05444853_10660 | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Lipoyl(octanoyl) transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.569 |
| SEM14612.1 | lolA | SAMN05444853_10658 | SAMN05444853_101164 | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Outer membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | 0.503 |
| SEM14612.1 | menA | SAMN05444853_10658 | SAMN05444853_103137 | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.823 |
| SEM14612.1 | rpsK | SAMN05444853_10658 | SAMN05444853_102144 | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | SSU ribosomal protein S11P; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.466 |
| SEM14612.1 | ubiA | SAMN05444853_10658 | SAMN05444853_10452 | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.883 |
| SEM14612.1 | ubiE | SAMN05444853_10658 | SAMN05444853_10468 | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.589 |
| SEM14612.1 | uppS | SAMN05444853_10658 | SAMN05444853_101114 | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.972 |
| SEM14634.1 | SEM14612.1 | SAMN05444853_10659 | SAMN05444853_10658 | Hypothetical protein; Belongs to the UPF0250 family. | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.568 |
| SEM14634.1 | lipA | SAMN05444853_10659 | SAMN05444853_10661 | Hypothetical protein; Belongs to the UPF0250 family. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.841 |
| SEM14634.1 | lipB | SAMN05444853_10659 | SAMN05444853_10660 | Hypothetical protein; Belongs to the UPF0250 family. | Lipoyl(octanoyl) transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.916 |
| SEM54732.1 | SEM14612.1 | SAMN05444853_12329 | SAMN05444853_10658 | Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.921 |
| SEM54732.1 | uppS | SAMN05444853_12329 | SAMN05444853_101114 | Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.958 |
| lipA | SEM14612.1 | SAMN05444853_10661 | SAMN05444853_10658 | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.514 |
| lipA | SEM14634.1 | SAMN05444853_10661 | SAMN05444853_10659 | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Hypothetical protein; Belongs to the UPF0250 family. | 0.841 |
| lipA | lipB | SAMN05444853_10661 | SAMN05444853_10660 | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Lipoyl(octanoyl) transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.999 |
| lipB | SEM14612.1 | SAMN05444853_10660 | SAMN05444853_10658 | Lipoyl(octanoyl) transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.569 |
| lipB | SEM14634.1 | SAMN05444853_10660 | SAMN05444853_10659 | Lipoyl(octanoyl) transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | Hypothetical protein; Belongs to the UPF0250 family. | 0.916 |