Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SEM14769.1Glutathione reductase (NADPH). (451 aa)    
Predicted Functional Partners:
SEM00531.1
Putative thioredoxin.
  
 
 0.960
SEL94475.1
Glutaredoxin-family domain-containing protein.
 
 0.957
SEM11943.1
Glutathione S-transferase; Belongs to the GST superfamily.
   
 0.914
SEM57961.1
Glutathione S-transferase.
   
 0.912
SEM19556.1
Peptidyl-prolyl cis-trans isomerase D.
  
 0.829
SEM39673.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.829
SEM35448.1
2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.823
SEM35426.1
2-oxoglutarate dehydrogenase E1 component.
  
 0.782
SEM01725.1
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
  
 
 0.691
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.642
Your Current Organism:
Pasteurella skyensis
NCBI taxonomy Id: 97481
Other names: DSM 24204, NCIMB 13593, NCTC 13204, P. skyensis, Pasteurella skyensis Birkbeck et al. 2002, strain 95A1
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