| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MetQ | SEM20151.1 | SAMN05444853_10827 | SAMN05444853_10824 | D-methionine transport system substrate-binding protein; Belongs to the nlpA lipoprotein family. | Two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB. | 0.481 |
| MetQ | SEM20205.1 | SAMN05444853_10827 | SAMN05444853_10826 | D-methionine transport system substrate-binding protein; Belongs to the nlpA lipoprotein family. | D-methionine transport system permease protein. | 0.999 |
| MetQ | SEM22373.1 | SAMN05444853_10827 | SAMN05444853_1094 | D-methionine transport system substrate-binding protein; Belongs to the nlpA lipoprotein family. | Glutamate synthase (NADPH/NADH) small chain. | 0.407 |
| MetQ | SEM52619.1 | SAMN05444853_10827 | SAMN05444853_12213 | D-methionine transport system substrate-binding protein; Belongs to the nlpA lipoprotein family. | Aspartate kinase; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.534 |
| MetQ | ilvC | SAMN05444853_10827 | SAMN05444853_1369 | D-methionine transport system substrate-binding protein; Belongs to the nlpA lipoprotein family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.461 |
| MetQ | metK | SAMN05444853_10827 | SAMN05444853_10370 | D-methionine transport system substrate-binding protein; Belongs to the nlpA lipoprotein family. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.449 |
| MetQ | metN | SAMN05444853_10827 | SAMN05444853_10825 | D-methionine transport system substrate-binding protein; Belongs to the nlpA lipoprotein family. | D-methionine transport system ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.997 |
| MetQ | sstT | SAMN05444853_10827 | SAMN05444853_10386 | D-methionine transport system substrate-binding protein; Belongs to the nlpA lipoprotein family. | Serine/threonine transporter; Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system). Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | 0.621 |
| SEM20151.1 | MetQ | SAMN05444853_10824 | SAMN05444853_10827 | Two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB. | D-methionine transport system substrate-binding protein; Belongs to the nlpA lipoprotein family. | 0.481 |
| SEM20151.1 | SEM20205.1 | SAMN05444853_10824 | SAMN05444853_10826 | Two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB. | D-methionine transport system permease protein. | 0.513 |
| SEM20151.1 | SEM52619.1 | SAMN05444853_10824 | SAMN05444853_12213 | Two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB. | Aspartate kinase; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.662 |
| SEM20151.1 | metN | SAMN05444853_10824 | SAMN05444853_10825 | Two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB. | D-methionine transport system ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.557 |
| SEM20205.1 | MetQ | SAMN05444853_10826 | SAMN05444853_10827 | D-methionine transport system permease protein. | D-methionine transport system substrate-binding protein; Belongs to the nlpA lipoprotein family. | 0.999 |
| SEM20205.1 | SEM20151.1 | SAMN05444853_10826 | SAMN05444853_10824 | D-methionine transport system permease protein. | Two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB. | 0.513 |
| SEM20205.1 | metN | SAMN05444853_10826 | SAMN05444853_10825 | D-methionine transport system permease protein. | D-methionine transport system ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.999 |
| SEM22373.1 | MetQ | SAMN05444853_1094 | SAMN05444853_10827 | Glutamate synthase (NADPH/NADH) small chain. | D-methionine transport system substrate-binding protein; Belongs to the nlpA lipoprotein family. | 0.407 |
| SEM52619.1 | MetQ | SAMN05444853_12213 | SAMN05444853_10827 | Aspartate kinase; In the C-terminal section; belongs to the homoserine dehydrogenase family. | D-methionine transport system substrate-binding protein; Belongs to the nlpA lipoprotein family. | 0.534 |
| SEM52619.1 | SEM20151.1 | SAMN05444853_12213 | SAMN05444853_10824 | Aspartate kinase; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB. | 0.662 |
| SEM52619.1 | ilvC | SAMN05444853_12213 | SAMN05444853_1369 | Aspartate kinase; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.721 |
| SEM52619.1 | metK | SAMN05444853_12213 | SAMN05444853_10370 | Aspartate kinase; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.687 |
