Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SEM19611.1Membrane fusion protein, multidrug efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (404 aa)    
Predicted Functional Partners:
SEM19640.1
Multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.999
SEM00929.1
Outer membrane protein TolC.
 
 0.976
SEL89163.1
Efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family.
 
 
 0.951
SEM19582.1
TetR/AcrR family transcriptional regulator, multidrug resistance operon repressor.
 
   
 0.810
lolD
Lipoprotein-releasing system ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.
  
 
 0.666
SEL90422.1
Outer membrane protein TolC.
  
 
 0.656
SEM00951.1
HlyD family secretion protein.
 
   
 0.548
SEM20151.1
Two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB.
  
  
 0.544
cysS
cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.472
SEM00983.1
ABC-2 type transport system permease protein.
 
   
 0.409
Your Current Organism:
Pasteurella skyensis
NCBI taxonomy Id: 97481
Other names: DSM 24204, NCIMB 13593, NCTC 13204, P. skyensis, Pasteurella skyensis Birkbeck et al. 2002, strain 95A1
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