Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SEM19640.1Multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1030 aa)    
Predicted Functional Partners:
SEM19611.1
Membrane fusion protein, multidrug efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.999
SEM00929.1
Outer membrane protein TolC.
 
 0.964
SEL89163.1
Efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family.
 
 
 0.830
SEM19582.1
TetR/AcrR family transcriptional regulator, multidrug resistance operon repressor.
     
 0.746
yajC
Preprotein translocase subunit YajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.
    
 
 0.593
SEM20151.1
Two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB.
   
 
 0.540
SEL90422.1
Outer membrane protein TolC.
  
 
 0.532
SEM00951.1
HlyD family secretion protein.
 
   
 0.525
cysS
cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.452
Your Current Organism:
Pasteurella skyensis
NCBI taxonomy Id: 97481
Other names: DSM 24204, NCIMB 13593, NCTC 13204, P. skyensis, Pasteurella skyensis Birkbeck et al. 2002, strain 95A1
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