STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEM20977.1HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes. (419 aa)    
Predicted Functional Partners:
cobB
NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily.
   
 
  0.990
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
    
 0.946
SEM41126.1
Nicotinate phosphoribosyltransferase; Belongs to the NAPRTase family.
    
 0.945
SEM57526.1
Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family.
    
 0.945
SEM53383.1
Tetratricopeptide repeat-containing protein.
  
  
 0.918
SEL90122.1
Putative hydrolase of the HAD superfamily.
    
 0.912
SEM17535.1
Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family.
   
    0.912
UshA
5'-nucleotidase / UDP-sugar diphosphatase; Belongs to the 5'-nucleotidase family.
     
 0.911
deoD
Purine-nucleoside phosphorylase.
    
 0.911
SEM10750.1
ATP diphosphatase.
     
 0.902
Your Current Organism:
Pasteurella skyensis
NCBI taxonomy Id: 97481
Other names: DSM 24204, NCIMB 13593, NCTC 13204, P. skyensis, Pasteurella skyensis Birkbeck et al. 2002, strain 95A1
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