Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SEM23593.1DNA repair protein RadC; Belongs to the UPF0758 family. (222 aa)    
Predicted Functional Partners:
SEM35398.1
Competence protein ComEC.
 
  
 0.712
SEM59435.1
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
  
  
 0.700
SEL96375.1
comF family protein.
 
    0.582
rpmB
LSU ribosomal protein L28P; Belongs to the bacterial ribosomal protein bL28 family.
     
 0.534
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
   
 0.512
dut
dUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
     
 0.495
SEM36485.1
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
   
 0.488
rpmG-2
LSU ribosomal protein L33P; Belongs to the bacterial ribosomal protein bL33 family.
       0.486
SEM23618.1
MFS transporter, DHA1 family, bicyclomycin/chloramphenicol resistance protein.
     
 0.483
SEL94947.1
DNA processing protein.
  
  
 0.482
Your Current Organism:
Pasteurella skyensis
NCBI taxonomy Id: 97481
Other names: DSM 24204, NCIMB 13593, NCTC 13204, P. skyensis, Pasteurella skyensis Birkbeck et al. 2002, strain 95A1
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