| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SEM11690.1 | rdgC | SAMN05444853_10582 | SAMN05444853_11018 | Exodeoxyribonuclease-1. | Recombination associated protein RdgC; May be involved in recombination; Belongs to the RdgC family. | 0.595 |
| SEM25274.1 | SEM25614.1 | SAMN05444853_11019 | SAMN05444853_11020 | dATP pyrophosphohydrolase. | DNA-binding regulatory protein, YebC/PmpR family. | 0.838 |
| SEM25274.1 | SEM25676.1 | SAMN05444853_11019 | SAMN05444853_11022 | dATP pyrophosphohydrolase. | TatD DNase family protein. | 0.626 |
| SEM25274.1 | rdgC | SAMN05444853_11019 | SAMN05444853_11018 | dATP pyrophosphohydrolase. | Recombination associated protein RdgC; May be involved in recombination; Belongs to the RdgC family. | 0.773 |
| SEM25274.1 | ruvC | SAMN05444853_11019 | SAMN05444853_11021 | dATP pyrophosphohydrolase. | Holliday junction endonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.629 |
| SEM25614.1 | SEM25274.1 | SAMN05444853_11020 | SAMN05444853_11019 | DNA-binding regulatory protein, YebC/PmpR family. | dATP pyrophosphohydrolase. | 0.838 |
| SEM25614.1 | SEM25676.1 | SAMN05444853_11020 | SAMN05444853_11022 | DNA-binding regulatory protein, YebC/PmpR family. | TatD DNase family protein. | 0.574 |
| SEM25614.1 | rdgC | SAMN05444853_11020 | SAMN05444853_11018 | DNA-binding regulatory protein, YebC/PmpR family. | Recombination associated protein RdgC; May be involved in recombination; Belongs to the RdgC family. | 0.714 |
| SEM25614.1 | ruvC | SAMN05444853_11020 | SAMN05444853_11021 | DNA-binding regulatory protein, YebC/PmpR family. | Holliday junction endonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.713 |
| SEM25676.1 | SEM25274.1 | SAMN05444853_11022 | SAMN05444853_11019 | TatD DNase family protein. | dATP pyrophosphohydrolase. | 0.626 |
| SEM25676.1 | SEM25614.1 | SAMN05444853_11022 | SAMN05444853_11020 | TatD DNase family protein. | DNA-binding regulatory protein, YebC/PmpR family. | 0.574 |
| SEM25676.1 | rdgC | SAMN05444853_11022 | SAMN05444853_11018 | TatD DNase family protein. | Recombination associated protein RdgC; May be involved in recombination; Belongs to the RdgC family. | 0.521 |
| SEM25676.1 | ruvC | SAMN05444853_11022 | SAMN05444853_11021 | TatD DNase family protein. | Holliday junction endonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.772 |
| SEM59395.1 | rdgC | SAMN05444853_12714 | SAMN05444853_11018 | Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. | Recombination associated protein RdgC; May be involved in recombination; Belongs to the RdgC family. | 0.544 |
| gltX | rdgC | SAMN05444853_1114 | SAMN05444853_11018 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | Recombination associated protein RdgC; May be involved in recombination; Belongs to the RdgC family. | 0.528 |
| grpE | htpG | SAMN05444853_11068 | SAMN05444853_103116 | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity. | 0.838 |
| grpE | radA | SAMN05444853_11068 | SAMN05444853_11841 | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | DNA repair protein RadA/Sms; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.522 |
| grpE | rdgC | SAMN05444853_11068 | SAMN05444853_11018 | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | Recombination associated protein RdgC; May be involved in recombination; Belongs to the RdgC family. | 0.512 |
| htpG | grpE | SAMN05444853_103116 | SAMN05444853_11068 | Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.838 |
| htpG | radA | SAMN05444853_103116 | SAMN05444853_11841 | Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity. | DNA repair protein RadA/Sms; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.512 |
