Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SEM39504.1DNA ligase-1. (269 aa)    
Predicted Functional Partners:
SEM36611.1
DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...]
   
 0.908
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.897
SEM26114.1
Exodeoxyribonuclease-3.
  
 
 0.796
SEM34497.1
Hypothetical protein.
   
 0.758
SEM18235.1
DNA polymerase-3 subunit delta'.
   
 0.690
SEM39475.1
Phosphonoacetate hydrolase.
       0.590
SEM39530.1
2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase; Belongs to the 5'-nucleotidase family.
       0.480
SEM22408.1
D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase.
   
 0.463
SEM49688.1
D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase.
   
 0.463
SEM39580.1
Helix-turn-helix.
 
     0.445
Your Current Organism:
Pasteurella skyensis
NCBI taxonomy Id: 97481
Other names: DSM 24204, NCIMB 13593, NCTC 13204, P. skyensis, Pasteurella skyensis Birkbeck et al. 2002, strain 95A1
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