| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SEM02623.1 | SEM40467.1 | SAMN05444853_10397 | SAMN05444853_11610 | Formate transporter. | Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | 0.684 |
| SEM22339.1 | SEM40467.1 | SAMN05444853_1093 | SAMN05444853_11610 | Glutamate synthase (NADPH/NADH) large chain. | Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | 0.507 |
| SEM22339.1 | guaB | SAMN05444853_1093 | SAMN05444853_101124 | Glutamate synthase (NADPH/NADH) large chain. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.625 |
| SEM40440.1 | SEM40467.1 | SAMN05444853_1169 | SAMN05444853_11610 | Peptide/bleomycin uptake transporter. | Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | 0.539 |
| SEM40467.1 | SEM02623.1 | SAMN05444853_11610 | SAMN05444853_10397 | Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | Formate transporter. | 0.684 |
| SEM40467.1 | SEM22339.1 | SAMN05444853_11610 | SAMN05444853_1093 | Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | Glutamate synthase (NADPH/NADH) large chain. | 0.507 |
| SEM40467.1 | SEM40440.1 | SAMN05444853_11610 | SAMN05444853_1169 | Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | Peptide/bleomycin uptake transporter. | 0.539 |
| SEM40467.1 | apt | SAMN05444853_11610 | SAMN05444853_101144 | Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.459 |
| SEM40467.1 | gpt | SAMN05444853_11610 | SAMN05444853_11168 | Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.459 |
| SEM40467.1 | guaB | SAMN05444853_11610 | SAMN05444853_101124 | Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.408 |
| apt | SEM40467.1 | SAMN05444853_101144 | SAMN05444853_11610 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | 0.459 |
| apt | gpt | SAMN05444853_101144 | SAMN05444853_11168 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.426 |
| gpt | SEM40467.1 | SAMN05444853_11168 | SAMN05444853_11610 | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | 0.459 |
| gpt | apt | SAMN05444853_11168 | SAMN05444853_101144 | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.426 |
| gpt | guaB | SAMN05444853_11168 | SAMN05444853_101124 | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.924 |
| guaB | SEM22339.1 | SAMN05444853_101124 | SAMN05444853_1093 | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Glutamate synthase (NADPH/NADH) large chain. | 0.625 |
| guaB | SEM40467.1 | SAMN05444853_101124 | SAMN05444853_11610 | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | 0.408 |
| guaB | gpt | SAMN05444853_101124 | SAMN05444853_11168 | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.924 |