node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEM45754.1 | SEM45794.1 | SAMN05444853_1192 | SAMN05444853_1193 | DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains. | DNA repair protein RecN (Recombination protein N); May be involved in recombinational repair of damaged DNA. | 0.467 |
SEM45754.1 | murQ | SAMN05444853_1192 | SAMN05444853_10519 | DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains. | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. | 0.548 |
SEM45754.1 | nagB | SAMN05444853_1192 | SAMN05444853_1191 | DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains. | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.740 |
SEM45754.1 | nanA | SAMN05444853_1192 | SAMN05444853_12822 | DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains. | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. | 0.651 |
SEM45754.1 | nanE | SAMN05444853_1192 | SAMN05444853_12820 | DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains. | N-acylglucosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). | 0.692 |
SEM45794.1 | SEM45754.1 | SAMN05444853_1193 | SAMN05444853_1192 | DNA repair protein RecN (Recombination protein N); May be involved in recombinational repair of damaged DNA. | DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains. | 0.467 |
SEM45794.1 | nagB | SAMN05444853_1193 | SAMN05444853_1191 | DNA repair protein RecN (Recombination protein N); May be involved in recombinational repair of damaged DNA. | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.444 |
murQ | SEM45754.1 | SAMN05444853_10519 | SAMN05444853_1192 | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. | DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains. | 0.548 |
murQ | nanE | SAMN05444853_10519 | SAMN05444853_12820 | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. | N-acylglucosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). | 0.906 |
nagB | SEM45754.1 | SAMN05444853_1191 | SAMN05444853_1192 | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains. | 0.740 |
nagB | SEM45794.1 | SAMN05444853_1191 | SAMN05444853_1193 | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | DNA repair protein RecN (Recombination protein N); May be involved in recombinational repair of damaged DNA. | 0.444 |
nagB | nanE | SAMN05444853_1191 | SAMN05444853_12820 | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | N-acylglucosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). | 0.650 |
nanA | SEM45754.1 | SAMN05444853_12822 | SAMN05444853_1192 | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. | DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains. | 0.651 |
nanA | nanE | SAMN05444853_12822 | SAMN05444853_12820 | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. | N-acylglucosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). | 0.975 |
nanE | SEM45754.1 | SAMN05444853_12820 | SAMN05444853_1192 | N-acylglucosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). | DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains. | 0.692 |
nanE | murQ | SAMN05444853_12820 | SAMN05444853_10519 | N-acylglucosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. | 0.906 |
nanE | nagB | SAMN05444853_12820 | SAMN05444853_1191 | N-acylglucosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.650 |
nanE | nanA | SAMN05444853_12820 | SAMN05444853_12822 | N-acylglucosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. | 0.975 |