Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
deoDPurine-nucleoside phosphorylase. (237 aa)    
Predicted Functional Partners:
SEM20977.1
HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes.
    
 0.931
gpt
Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
    
 0.922
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
 0.920
UshA
5'-nucleotidase / UDP-sugar diphosphatase; Belongs to the 5'-nucleotidase family.
    
 0.910
cobB
NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily.
    
 0.909
SEM21188.1
Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
 0.907
SEM41126.1
Nicotinate phosphoribosyltransferase; Belongs to the NAPRTase family.
     
 0.906
SEM57526.1
Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family.
     
 0.906
SEM39530.1
2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase; Belongs to the 5'-nucleotidase family.
    
 0.902
SEL89790.1
Conserved hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family.
     
  0.900
Your Current Organism:
Pasteurella skyensis
NCBI taxonomy Id: 97481
Other names: DSM 24204, NCIMB 13593, NCTC 13204, P. skyensis, Pasteurella skyensis Birkbeck et al. 2002, strain 95A1
Server load: low (38%) [HD]