| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SEM35040.1 | SEM35662.1 | SAMN05444853_11346 | SAMN05444853_11369 | Negative regulator of replication initiation SeqA; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated; Belongs to the SeqA family. | Hypothetical protein; Belongs to the UPF0352 family. | 0.773 |
| SEM35040.1 | SEM36720.1 | SAMN05444853_11346 | SAMN05444853_11424 | Negative regulator of replication initiation SeqA; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated; Belongs to the SeqA family. | Hypothetical protein. | 0.645 |
| SEM35040.1 | SEM65043.1 | SAMN05444853_11346 | SAMN05444853_1366 | Negative regulator of replication initiation SeqA; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated; Belongs to the SeqA family. | Acetolactate synthase, small subunit. | 0.577 |
| SEM35040.1 | SEM66782.1 | SAMN05444853_11346 | SAMN05444853_1404 | Negative regulator of replication initiation SeqA; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated; Belongs to the SeqA family. | Alternative ribosome-rescue factor. | 0.469 |
| SEM35040.1 | SEM67500.1 | SAMN05444853_11346 | SAMN05444853_1422 | Negative regulator of replication initiation SeqA; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated; Belongs to the SeqA family. | Hypothetical protein. | 0.652 |
| SEM35040.1 | priB | SAMN05444853_11346 | SAMN05444853_11444 | Negative regulator of replication initiation SeqA; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated; Belongs to the SeqA family. | Restart primosome assembly protein PriB; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family. | 0.642 |
| SEM35040.1 | zapB | SAMN05444853_11346 | SAMN05444853_10586 | Negative regulator of replication initiation SeqA; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated; Belongs to the SeqA family. | Cell division protein ZapB; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. | 0.698 |
| SEM35662.1 | SEM35040.1 | SAMN05444853_11369 | SAMN05444853_11346 | Hypothetical protein; Belongs to the UPF0352 family. | Negative regulator of replication initiation SeqA; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated; Belongs to the SeqA family. | 0.773 |
| SEM35662.1 | SEM59590.1 | SAMN05444853_11369 | SAMN05444853_12720 | Hypothetical protein; Belongs to the UPF0352 family. | Hypothetical protein; Belongs to the UPF0231 family. | 0.536 |
| SEM35662.1 | SEM65043.1 | SAMN05444853_11369 | SAMN05444853_1366 | Hypothetical protein; Belongs to the UPF0352 family. | Acetolactate synthase, small subunit. | 0.703 |
| SEM35662.1 | SEM66782.1 | SAMN05444853_11369 | SAMN05444853_1404 | Hypothetical protein; Belongs to the UPF0352 family. | Alternative ribosome-rescue factor. | 0.451 |
| SEM35662.1 | SEM67500.1 | SAMN05444853_11369 | SAMN05444853_1422 | Hypothetical protein; Belongs to the UPF0352 family. | Hypothetical protein. | 0.606 |
| SEM35662.1 | zapB | SAMN05444853_11369 | SAMN05444853_10586 | Hypothetical protein; Belongs to the UPF0352 family. | Cell division protein ZapB; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. | 0.761 |
| SEM36720.1 | SEM35040.1 | SAMN05444853_11424 | SAMN05444853_11346 | Hypothetical protein. | Negative regulator of replication initiation SeqA; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated; Belongs to the SeqA family. | 0.645 |
| SEM36720.1 | SEM66782.1 | SAMN05444853_11424 | SAMN05444853_1404 | Hypothetical protein. | Alternative ribosome-rescue factor. | 0.408 |
| SEM36720.1 | SEM67500.1 | SAMN05444853_11424 | SAMN05444853_1422 | Hypothetical protein. | Hypothetical protein. | 0.604 |
| SEM36720.1 | priB | SAMN05444853_11424 | SAMN05444853_11444 | Hypothetical protein. | Restart primosome assembly protein PriB; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family. | 0.530 |
| SEM59590.1 | SEM35662.1 | SAMN05444853_12720 | SAMN05444853_11369 | Hypothetical protein; Belongs to the UPF0231 family. | Hypothetical protein; Belongs to the UPF0352 family. | 0.536 |
| SEM59590.1 | SEM65043.1 | SAMN05444853_12720 | SAMN05444853_1366 | Hypothetical protein; Belongs to the UPF0231 family. | Acetolactate synthase, small subunit. | 0.763 |
| SEM59590.1 | SEM67500.1 | SAMN05444853_12720 | SAMN05444853_1422 | Hypothetical protein; Belongs to the UPF0231 family. | Hypothetical protein. | 0.629 |