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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HBBHemoglobin subunit beta; Belongs to the globin family. (147 aa)    
Predicted Functional Partners:
LOC111185089
Hemoglobin subunit alpha; Belongs to the globin family.
  
0.999
LOC111179563
Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.
   
 0.989
HBQ1
Hemoglobin subunit theta-1-like; Belongs to the globin family.
  
0.935
HBZ
Hemoglobin subunit zeta; Belongs to the globin family.
  
0.910
HBM
Hemoglobin subunit mu; Belongs to the globin family.
   
0.907
MASP1
Mannan-binding lectin serine protease 1 isoform X1; Belongs to the peptidase S1 family.
   
 0.732
AHSP
Alpha-hemoglobin-stabilizing protein.
   
 
 0.633
LOC111176714
Scavenger receptor cysteine-rich type 1 protein M130 isoform X1.
     
 0.612
EDNRB
Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family.
      
 0.602
LOC111171052
Cytochrome b5 reductase 4-like.
   
 0.601
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.