Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HSCBIron-sulfur cluster co-chaperone protein HscB, mitochondrial isoform X1. (235 aa)    
Predicted Functional Partners:
ISCU
Iron-sulfur cluster assembly enzyme ISCU, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.
  
 
 0.949
HSPA9
Stress-70 protein, mitochondrial; Belongs to the heat shock protein 70 family.
    
 0.943
LOC111181215
Succinate dehydrogenase assembly factor 1, mitochondrial-like; Belongs to the complex I LYR family.
    
 
 0.834
SDHB
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
   
 
 0.827
NFS1
Cysteine desulfurase, mitochondrial.
  
 
 0.782
GLRX5
Glutaredoxin-related protein 5, mitochondrial.
    
 0.774
LOC111162798
Cytochrome b-c1 complex subunit 9.
      
 0.736
GRPEL1
GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.
    
 0.697
LYRM7
Complex III assembly factor LYRM7; Belongs to the complex I LYR family.
    
 0.679
ABCB7
ATP-binding cassette sub-family B member 7, mitochondrial.
    
 
 0.648
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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