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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISCUIron-sulfur cluster assembly enzyme ISCU, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (167 aa)    
Predicted Functional Partners:
NFS1
Cysteine desulfurase, mitochondrial.
 
 0.999
FXN
Frataxin, mitochondrial.
    
 0.998
MOCOS
Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
  
 0.998
SCLY
Selenocysteine lyase isoform X1.
 
 0.995
LYRM4
LYR motif-containing protein 4; Belongs to the complex I LYR family.
    
 0.988
ISCA2
Iron-sulfur cluster assembly 2 homolog, mitochondrial isoform X1.
  
  
 0.920
FDX1L
Ferredoxin-2, mitochondrial isoform X2.
  
 0.918
ISCA1
Iron-sulfur cluster assembly 1 homolog, mitochondrial isoform X1.
  
  
 0.901
FDX1
Adrenodoxin, mitochondrial.
 
 0.894
NFU1
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial isoform X1.
  
 
 0.830
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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