Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISCUIron-sulfur cluster assembly enzyme ISCU, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (167 aa)    
Predicted Functional Partners:
NFS1
Cysteine desulfurase, mitochondrial.
 
 0.999
FXN
Frataxin, mitochondrial.
    
 0.993
LYRM4
LYR motif-containing protein 4; Belongs to the complex I LYR family.
    
 0.993
MOCOS
Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
  
 0.989
SCLY
Selenocysteine lyase isoform X1.
 
 0.978
FDX1L
Ferredoxin-2, mitochondrial isoform X2.
  
 0.953
ISCA2
Iron-sulfur cluster assembly 2 homolog, mitochondrial isoform X1.
  
 
 0.952
HSCB
Iron-sulfur cluster co-chaperone protein HscB, mitochondrial isoform X1.
  
 
 0.949
FDX1
Adrenodoxin, mitochondrial.
 
 0.932
HSPA9
Stress-70 protein, mitochondrial; Belongs to the heat shock protein 70 family.
  
 0.929
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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