Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RAB42Putative Ras-related protein Rab-42. (220 aa)    
Predicted Functional Partners:
CHM
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
    
 0.640
ITSN2
Intersectin-2 isoform X1.
    
 0.573
RAB14
Ras-related protein Rab-14.
    
  0.561
LOC111178618
Collagen alpha-1(I) chain-like.
    
 0.527
RABGGTA
Geranylgeranyl transferase type-2 subunit alpha isoform X1.
    
 0.487
PTAR1
Protein prenyltransferase alpha subunit repeat-containing protein 1.
    
 0.487
COG8
Conserved oligomeric Golgi complex subunit 8; Belongs to the COG8 family.
    
  0.459
RABGGTB
Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX.
    
 0.458
TMEM71
Transmembrane protein 71 isoform X1.
      
 0.451
COG6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
    
 0.446
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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