| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACKR3 | CNR2 | A0A2Y9MS64 | A0A2Y9LDT7 | Atypical chemokine receptor 3 isoform X1; Belongs to the G-protein coupled receptor 1 family. | Cannabinoid receptor 2 isoform X1; Belongs to the G-protein coupled receptor 1 family. | 0.488 |
| CNR1 | CNR2 | A0A2Y9LEV9 | A0A2Y9LDT7 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Cannabinoid receptor 2 isoform X1; Belongs to the G-protein coupled receptor 1 family. | 0.946 |
| CNR1 | FAAH | A0A2Y9LEV9 | A0A2Y9NPR7 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Fatty-acid amide hydrolase 1 isoform X1. | 0.760 |
| CNR1 | GPR18 | A0A2Y9LEV9 | A0A2Y9NMH6 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | N-arachidonyl glycine receptor; Belongs to the G-protein coupled receptor 1 family. | 0.629 |
| CNR1 | GPR55 | A0A2Y9LEV9 | A0A2Y9MMW4 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | G-protein coupled receptor 55 isoform X1; Belongs to the G-protein coupled receptor 1 family. | 0.718 |
| CNR1 | LOC111176429 | A0A2Y9LEV9 | A0A2Y9NCC2 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | G-protein coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. | 0.522 |
| CNR1 | LOC111186949 | A0A2Y9LEV9 | A0A2Y9Q3U1 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Hydroxycarboxylic acid receptor 2-like; Belongs to the G-protein coupled receptor 1 family. | 0.507 |
| CNR1 | MTNR1B | A0A2Y9LEV9 | A0A2Y9M5V6 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | LOW QUALITY PROTEIN: melatonin receptor type 1B. | 0.508 |
| CNR1 | NAPEPLD | A0A2Y9LEV9 | A0A2Y9LL11 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D isoform X1. | 0.603 |
| CNR2 | ACKR3 | A0A2Y9LDT7 | A0A2Y9MS64 | Cannabinoid receptor 2 isoform X1; Belongs to the G-protein coupled receptor 1 family. | Atypical chemokine receptor 3 isoform X1; Belongs to the G-protein coupled receptor 1 family. | 0.488 |
| CNR2 | CNR1 | A0A2Y9LDT7 | A0A2Y9LEV9 | Cannabinoid receptor 2 isoform X1; Belongs to the G-protein coupled receptor 1 family. | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | 0.946 |
| CNR2 | FAAH | A0A2Y9LDT7 | A0A2Y9NPR7 | Cannabinoid receptor 2 isoform X1; Belongs to the G-protein coupled receptor 1 family. | Fatty-acid amide hydrolase 1 isoform X1. | 0.585 |
| CNR2 | GPR18 | A0A2Y9LDT7 | A0A2Y9NMH6 | Cannabinoid receptor 2 isoform X1; Belongs to the G-protein coupled receptor 1 family. | N-arachidonyl glycine receptor; Belongs to the G-protein coupled receptor 1 family. | 0.635 |
| CNR2 | GPR55 | A0A2Y9LDT7 | A0A2Y9MMW4 | Cannabinoid receptor 2 isoform X1; Belongs to the G-protein coupled receptor 1 family. | G-protein coupled receptor 55 isoform X1; Belongs to the G-protein coupled receptor 1 family. | 0.655 |
| CNR2 | LOC111176429 | A0A2Y9LDT7 | A0A2Y9NCC2 | Cannabinoid receptor 2 isoform X1; Belongs to the G-protein coupled receptor 1 family. | G-protein coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. | 0.538 |
| CNR2 | LOC111186949 | A0A2Y9LDT7 | A0A2Y9Q3U1 | Cannabinoid receptor 2 isoform X1; Belongs to the G-protein coupled receptor 1 family. | Hydroxycarboxylic acid receptor 2-like; Belongs to the G-protein coupled receptor 1 family. | 0.559 |
| CNR2 | MTNR1B | A0A2Y9LDT7 | A0A2Y9M5V6 | Cannabinoid receptor 2 isoform X1; Belongs to the G-protein coupled receptor 1 family. | LOW QUALITY PROTEIN: melatonin receptor type 1B. | 0.531 |
| CNR2 | NAPEPLD | A0A2Y9LDT7 | A0A2Y9LL11 | Cannabinoid receptor 2 isoform X1; Belongs to the G-protein coupled receptor 1 family. | N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D isoform X1. | 0.514 |
| CNR2 | PTGIR | A0A2Y9LDT7 | A0A2Y9P713 | Cannabinoid receptor 2 isoform X1; Belongs to the G-protein coupled receptor 1 family. | Prostacyclin receptor; Belongs to the G-protein coupled receptor 1 family. | 0.467 |
| FAAH | CNR1 | A0A2Y9NPR7 | A0A2Y9LEV9 | Fatty-acid amide hydrolase 1 isoform X1. | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | 0.760 |