| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BTK | EDN1 | A0A2Y9NR66 | A0A2Y9PHR8 | Tyrosine-protein kinase. | Endothelin-1. | 0.512 |
| BTK | F2 | A0A2Y9NR66 | A0A2Y9PXE8 | Tyrosine-protein kinase. | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.548 |
| BTK | F2RL1 | A0A2Y9NR66 | A0A2Y9LEA6 | Tyrosine-protein kinase. | Proteinase-activated receptor 2. | 0.532 |
| BTK | GNAQ | A0A2Y9NR66 | A0A2Y9NIQ8 | Tyrosine-protein kinase. | Guanine nucleotide-binding protein G(Q) subunit alpha isoform X1. | 0.434 |
| BTK | KNG1 | A0A2Y9NR66 | A0A2Y9N2V9 | Tyrosine-protein kinase. | Kininogen-1 isoform X1. | 0.514 |
| EDN1 | BTK | A0A2Y9PHR8 | A0A2Y9NR66 | Endothelin-1. | Tyrosine-protein kinase. | 0.512 |
| EDN1 | F2 | A0A2Y9PHR8 | A0A2Y9PXE8 | Endothelin-1. | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.525 |
| EDN1 | F2RL1 | A0A2Y9PHR8 | A0A2Y9LEA6 | Endothelin-1. | Proteinase-activated receptor 2. | 0.570 |
| EDN1 | GNAQ | A0A2Y9PHR8 | A0A2Y9NIQ8 | Endothelin-1. | Guanine nucleotide-binding protein G(Q) subunit alpha isoform X1. | 0.433 |
| EDN1 | KNG1 | A0A2Y9PHR8 | A0A2Y9N2V9 | Endothelin-1. | Kininogen-1 isoform X1. | 0.698 |
| F2 | BTK | A0A2Y9PXE8 | A0A2Y9NR66 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Tyrosine-protein kinase. | 0.548 |
| F2 | EDN1 | A0A2Y9PXE8 | A0A2Y9PHR8 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Endothelin-1. | 0.525 |
| F2 | F2RL1 | A0A2Y9PXE8 | A0A2Y9LEA6 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Proteinase-activated receptor 2. | 0.844 |
| F2 | KNG1 | A0A2Y9PXE8 | A0A2Y9N2V9 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Kininogen-1 isoform X1. | 0.738 |
| F2 | PLG | A0A2Y9PXE8 | A0A2Y9M5R2 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | 0.864 |
| F2RL1 | BTK | A0A2Y9LEA6 | A0A2Y9NR66 | Proteinase-activated receptor 2. | Tyrosine-protein kinase. | 0.532 |
| F2RL1 | EDN1 | A0A2Y9LEA6 | A0A2Y9PHR8 | Proteinase-activated receptor 2. | Endothelin-1. | 0.570 |
| F2RL1 | F2 | A0A2Y9LEA6 | A0A2Y9PXE8 | Proteinase-activated receptor 2. | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.844 |
| F2RL1 | GNAQ | A0A2Y9LEA6 | A0A2Y9NIQ8 | Proteinase-activated receptor 2. | Guanine nucleotide-binding protein G(Q) subunit alpha isoform X1. | 0.938 |
| F2RL1 | GZMA | A0A2Y9LEA6 | A0A2Y9QCP4 | Proteinase-activated receptor 2. | Granzyme A; Belongs to the peptidase S1 family. | 0.701 |