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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPICE1Spindle and centriole-associated protein 1. (857 aa)    
Predicted Functional Partners:
DRAXIN
Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
   
    0.793
CEP120
Centrosomal protein of 120 kDa isoform X1.
    
 
 0.715
POC5
Centrosomal protein POC5 isoform X1.
      
 0.699
CENPJ
Centromere protein J.
    
 
 0.627
TRIM65
Tripartite motif-containing protein 65 isoform X1.
    
 
 0.609
POC1B
POC1 centriolar protein homolog B isoform X1.
      
 0.604
POC1A
POC1 centriolar protein homolog A isoform X1.
      
 0.603
CNTROB
Centrobin isoform X1.
      
 0.517
MTHFSD
Methenyltetrahydrofolate synthase domain-containing protein isoform X1.
      
 0.506
CFAP36
Cilia- and flagella-associated protein 36.
      
 0.505
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.