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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OLIG2Oligodendrocyte transcription factor 2. (323 aa)    
Predicted Functional Partners:
NES
Nestin; Belongs to the intermediate filament family.
      
 0.828
PAX6
Paired box protein Pax-6 isoform X1.
   
 
 0.790
ASCL1
Achaete-scute homolog 1.
   
 
 0.769
SOX10
Transcription factor SOX-10.
   
 0.762
MYRF
Myelin regulatory factor isoform X1.
      
 0.758
ALDH1L1
10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
      
 0.756
GFAP
Glial fibrillary acidic protein isoform X1; Belongs to the intermediate filament family.
   
  
 0.751
MBP
Myelin basic protein isoform X1.
   
  
 0.743
CASP3
Caspase-3 isoform X1; Belongs to the peptidase C14A family.
      
 0.727
LOC111182889
LOW QUALITY PROTEIN: transcription factor SOX-9-like.
   
 0.706
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.