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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)    
Predicted Functional Partners:
RPS6
40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.
    
 0.992
MTOR
Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.
    
 0.992
EIF4B
Eukaryotic translation initiation factor 4B isoform X1.
   
 0.989
RPTOR
Regulatory-associated protein of mTOR isoform X7.
    
 0.983
MLST8
Target of rapamycin complex subunit LST8 isoform X1.
    
 0.974
PDPK1
3-phosphoinositide-dependent protein kinase 1 isoform X1.
  
 
0.974
AKT3
Non-specific serine/threonine protein kinase.
  
0.960
IRS1
Insulin receptor substrate 1.
   
 0.959
DEPTOR
DEP domain-containing mTOR-interacting protein isoform X1.
    
 0.958
AKT1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
  
0.956
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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