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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF4E3 ubiquitin-protein ligase RNF4 isoform X1. (213 aa)    
Predicted Functional Partners:
UBE2D1
Ubiquitin-conjugating enzyme E2 D1 isoform X1; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.933
SUMO2
Small ubiquitin-related modifier.
   
 
 0.871
SUMO1
Small ubiquitin-related modifier.
   
 
 0.864
SUMO3
Small ubiquitin-related modifier.
   
 
 0.848
RPS27A
ubiquitin-40S ribosomal protein S27a.
    
  0.791
KXD1
kxDL motif-containing protein 1 isoform X1.
    
   0.743
UBE2V2
Ubiquitin-conjugating enzyme E2 variant 2.
    
 0.723
PML
Protein PML isoform X1.
    
 
 0.700
UBE2N
Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.687
LOC111176111
Ubiquitin-conjugating enzyme E2 N-like.
   
 0.687
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.