close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC1111643115-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase; Belongs to the cytochrome P450 family. (511 aa)    
Predicted Functional Partners:
HSD3B7
3 beta-hydroxysteroid dehydrogenase type 7 isoform X1.
   
 0.968
LOC111171838
Sterol 26-hydroxylase, mitochondrial isoform X1; Belongs to the cytochrome P450 family.
     
0.959
AKR1D1
3-oxo-5-beta-steroid 4-dehydrogenase isoform X1.
   
 
 0.936
LSS
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
   
 0.759
CH25H
Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family.
   
 0.753
NR1H4
Bile acid receptor isoform X1.
   
 
 0.678
SQLE
Squalene monooxygenase.
   
 0.672
MSMO1
Methylsterol monooxygenase 1; Belongs to the sterol desaturase family.
   
 0.672
FAXDC2
Fatty acid hydroxylase domain-containing protein 2; Belongs to the sterol desaturase family.
   
 0.672
FDFT1
Squalene synthase isoform X1.
  
 
 0.668
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.