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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARNT2Aryl hydrocarbon receptor nuclear translocator 2 isoform X1. (717 aa)    
Predicted Functional Partners:
HIF1A
Hypoxia-inducible factor 1-alpha isoform X1.
   
0.993
EPAS1
Endothelial PAS domain-containing protein 1 isoform X1.
   
0.984
NPAS4
Neuronal PAS domain-containing protein 4.
    
0.982
AHR
Aryl hydrocarbon receptor; Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing [...]
   
0.959
ARNT
Aryl hydrocarbon receptor nuclear translocator isoform X1.
  
  
 
0.901
AHRR
Aryl hydrocarbon receptor repressor.
   
0.883
NPAS1
Neuronal PAS domain-containing protein 1.
   
0.827
HIF3A
Hypoxia-inducible factor 3-alpha isoform X1.
   
0.801
ZHX1
Zinc fingers and homeoboxes protein 1.
     
 0.747
SIM1
Single-minded homolog 1.
    
 
0.742
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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