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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPR101Probable G-protein coupled receptor 101; Belongs to the G-protein coupled receptor 1 family. (503 aa)    
Predicted Functional Partners:
PLAG1
Zinc finger protein PLAG1 isoform X1.
      
 0.808
OBSL1
Obscurin-like protein 1 isoform X2.
      
 0.808
EIF2AK3
Eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1.
      
 0.808
CDKN1B
Cyclin-dependent kinase inhibitor 1B.
      
 0.807
GRB10
Growth factor receptor-bound protein 10 isoform X1.
      
 0.807
CBS
Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
      
 0.796
FBN1
Fibrillin-1 isoform X1.
    
 0.796
GPC3
Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
      
 0.790
NOG
Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.
      
 0.788
KCNJ2
Inward rectifier potassium channel 2.
      
 0.734
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.