| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMD1 | DNMT1 | A0A2Y9LN26 | A0A2Y9M0U3 | S-adenosylmethionine decarboxylase proenzyme. | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.902 |
| AMD1 | DNMT3A | A0A2Y9LN26 | A0A2Y9N6V2 | S-adenosylmethionine decarboxylase proenzyme. | DNA (Cytosine-5)-methyltransferase 3A isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.900 |
| AMD1 | DNMT3B | A0A2Y9LN26 | A0A2Y9PS51 | S-adenosylmethionine decarboxylase proenzyme. | DNA (Cytosine-5)-methyltransferase 3B; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.900 |
| AMD1 | GJA10 | A0A2Y9LN26 | A0A2Y9LI30 | S-adenosylmethionine decarboxylase proenzyme. | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | 0.602 |
| AMD1 | MAT1A | A0A2Y9LN26 | A0A2Y9PUP0 | S-adenosylmethionine decarboxylase proenzyme. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.941 |
| AMD1 | MAT2A | A0A2Y9LN26 | A0A2Y9LR43 | S-adenosylmethionine decarboxylase proenzyme. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.933 |
| AMD1 | MAT2B | A0A2Y9LN26 | A0A2Y9PZE7 | S-adenosylmethionine decarboxylase proenzyme. | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | 0.916 |
| AMD1 | MMS22L | A0A2Y9LN26 | A0A2Y9LG99 | S-adenosylmethionine decarboxylase proenzyme. | Protein MMS22-like. | 0.602 |
| AMD1 | SMS | A0A2Y9LN26 | A0A2Y9M392 | S-adenosylmethionine decarboxylase proenzyme. | Spermine synthase. | 0.983 |
| AMD1 | SRM | A0A2Y9LN26 | A0A2Y9Q9W1 | S-adenosylmethionine decarboxylase proenzyme. | Spermidine synthase isoform X1; Belongs to the spermidine/spermine synthase family. | 0.983 |
| DNMT1 | AMD1 | A0A2Y9M0U3 | A0A2Y9LN26 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | S-adenosylmethionine decarboxylase proenzyme. | 0.902 |
| DNMT1 | DNMT3A | A0A2Y9M0U3 | A0A2Y9N6V2 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | DNA (Cytosine-5)-methyltransferase 3A isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.990 |
| DNMT1 | DNMT3B | A0A2Y9M0U3 | A0A2Y9PS51 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | DNA (Cytosine-5)-methyltransferase 3B; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.997 |
| DNMT1 | MAT1A | A0A2Y9M0U3 | A0A2Y9PUP0 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.915 |
| DNMT1 | MAT2A | A0A2Y9M0U3 | A0A2Y9LR43 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.921 |
| DNMT1 | MAT2B | A0A2Y9M0U3 | A0A2Y9PZE7 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | 0.928 |
| DNMT3A | AMD1 | A0A2Y9N6V2 | A0A2Y9LN26 | DNA (Cytosine-5)-methyltransferase 3A isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | S-adenosylmethionine decarboxylase proenzyme. | 0.900 |
| DNMT3A | DNMT1 | A0A2Y9N6V2 | A0A2Y9M0U3 | DNA (Cytosine-5)-methyltransferase 3A isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.990 |
| DNMT3A | DNMT3B | A0A2Y9N6V2 | A0A2Y9PS51 | DNA (Cytosine-5)-methyltransferase 3A isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | DNA (Cytosine-5)-methyltransferase 3B; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.989 |
| DNMT3A | MAT1A | A0A2Y9N6V2 | A0A2Y9PUP0 | DNA (Cytosine-5)-methyltransferase 3A isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.911 |