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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMPRSS3Transmembrane protease serine 3; Belongs to the peptidase S1 family. (453 aa)    
Predicted Functional Partners:
TMIE
Transmembrane inner ear expressed protein isoform X4.
      
 0.702
TPRN
Taperin.
      
 0.701
BOP1
Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
      
 0.690
TMC1
Transmembrane channel-like protein.
    
 0.640
GIPC3
PDZ domain-containing protein GIPC3.
   
 
 0.594
SERPINA5
Plasma serine protease inhibitor isoform X1; Belongs to the serpin family.
    
 0.562
MST1R
Macrophage-stimulating protein receptor isoform X1.
    
 0.561
MET
Hepatocyte growth factor receptor isoform X1.
    
 0.561
LOC111180818
Carcinoembryonic antigen-related cell adhesion molecule 1-like isoform X1.
   
 0.558
CD109
CD109 antigen isoform X1.
    
 0.556
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.