Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRTNsprT-like domain-containing protein Spartan isoform X1. (550 aa)    
Predicted Functional Partners:
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.984
VCP
Transitional endoplasmic reticulum ATPase isoform X1; Belongs to the AAA ATPase family.
   
 0.973
PPP2R3B
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X1.
   
    0.864
LOC111175271
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2-like isoform X1.
   
    0.864
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
   
    0.864
PPP2R3A
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X1.
   
    0.864
RFC1
Replication factor C subunit 1.
   
 0.839
FBXO28
F-box only protein 28.
   
    0.831
LOC111180044
F-box only protein 28-like isoform X1.
   
    0.831
NPLOC4
Nuclear protein localization protein 4 homolog isoform X1.
    
 0.820
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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