ADRA2C protein (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ADRA2C

alpha-2C adrenergic receptor. (458 aa)

Predicted Functional Partners:

GNA11

0.922

GNA12

0.922

GNAQ

0.922

GNA13

0.922

SFTPC

0.718

ADCY1

0.672

GNG2

0.647

GNB2

0.639

GNB5

0.634

GNAO1

0.588

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADRA2C	A0A2Y9PTI4	A0A2Y9LP97	Adenylate cyclase type 1.	alpha-2C adrenergic receptor.	0.672
ADCY1	GNAO1	A0A2Y9PTI4	A0A2Y9LWX7	Adenylate cyclase type 1.	Guanine nucleotide-binding protein G(O) subunit alpha isoform X1.	0.942
ADCY1	GNB2	A0A2Y9PTI4	A0A2Y9PED7	Adenylate cyclase type 1.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2.	0.875
ADCY1	GNB5	A0A2Y9PTI4	A0A2Y9NQP1	Adenylate cyclase type 1.	Guanine nucleotide-binding protein subunit beta-5 isoform X1.	0.843
ADCY1	GNG2	A0A2Y9PTI4	A0A2Y9NAL5	Adenylate cyclase type 1.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.832
ADRA2C	ADCY1	A0A2Y9LP97	A0A2Y9PTI4	alpha-2C adrenergic receptor.	Adenylate cyclase type 1.	0.672
ADRA2C	GNA11	A0A2Y9LP97	A0A2Y9LWA4	alpha-2C adrenergic receptor.	Guanine nucleotide-binding protein subunit alpha-11.	0.922
ADRA2C	GNA12	A0A2Y9LP97	A0A2Y9MQ45	alpha-2C adrenergic receptor.	Guanine nucleotide-binding protein subunit alpha-12 isoform X2.	0.922
ADRA2C	GNA13	A0A2Y9LP97	A0A2Y9PF13	alpha-2C adrenergic receptor.	Guanine nucleotide-binding protein subunit alpha-13.	0.922
ADRA2C	GNAO1	A0A2Y9LP97	A0A2Y9LWX7	alpha-2C adrenergic receptor.	Guanine nucleotide-binding protein G(O) subunit alpha isoform X1.	0.588
ADRA2C	GNAQ	A0A2Y9LP97	A0A2Y9NIQ8	alpha-2C adrenergic receptor.	Guanine nucleotide-binding protein G(Q) subunit alpha isoform X1.	0.922
ADRA2C	GNB2	A0A2Y9LP97	A0A2Y9PED7	alpha-2C adrenergic receptor.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2.	0.639
ADRA2C	GNB5	A0A2Y9LP97	A0A2Y9NQP1	alpha-2C adrenergic receptor.	Guanine nucleotide-binding protein subunit beta-5 isoform X1.	0.634
ADRA2C	GNG2	A0A2Y9LP97	A0A2Y9NAL5	alpha-2C adrenergic receptor.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.647
ADRA2C	SFTPC	A0A2Y9LP97	A0A2Y9M8S8	alpha-2C adrenergic receptor.	Pulmonary surfactant-associated protein C.	0.718
GNA11	ADRA2C	A0A2Y9LWA4	A0A2Y9LP97	Guanine nucleotide-binding protein subunit alpha-11.	alpha-2C adrenergic receptor.	0.922
GNA11	GNAQ	A0A2Y9LWA4	A0A2Y9NIQ8	Guanine nucleotide-binding protein subunit alpha-11.	Guanine nucleotide-binding protein G(Q) subunit alpha isoform X1.	0.946
GNA11	GNB2	A0A2Y9LWA4	A0A2Y9PED7	Guanine nucleotide-binding protein subunit alpha-11.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2.	0.849
GNA11	GNB5	A0A2Y9LWA4	A0A2Y9NQP1	Guanine nucleotide-binding protein subunit alpha-11.	Guanine nucleotide-binding protein subunit beta-5 isoform X1.	0.803
GNA11	GNG2	A0A2Y9LWA4	A0A2Y9NAL5	Guanine nucleotide-binding protein subunit alpha-11.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.819