| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DKC1 | METTL1 | A0A2Y9MLZ2 | A0A2Y9MZR9 | H/ACA ribonucleoprotein complex subunit 4. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | 0.668 |
| DKC1 | PUS3 | A0A2Y9MLZ2 | A0A2Y9LT95 | H/ACA ribonucleoprotein complex subunit 4. | tRNA pseudouridine(38/39) synthase. | 0.612 |
| DKC1 | QTRT1 | A0A2Y9MLZ2 | A0A2Y9LWZ0 | H/ACA ribonucleoprotein complex subunit 4. | Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] | 0.455 |
| DKC1 | QTRT2 | A0A2Y9MLZ2 | A0A2Y9LPB2 | H/ACA ribonucleoprotein complex subunit 4. | Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. | 0.455 |
| DKC1 | TRUB1 | A0A2Y9MLZ2 | A0A2Y9N592 | H/ACA ribonucleoprotein complex subunit 4. | Probable tRNA pseudouridine synthase 1 isoform X1. | 0.402 |
| METTL1 | DKC1 | A0A2Y9MZR9 | A0A2Y9MLZ2 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | H/ACA ribonucleoprotein complex subunit 4. | 0.668 |
| METTL1 | PUS3 | A0A2Y9MZR9 | A0A2Y9LT95 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | tRNA pseudouridine(38/39) synthase. | 0.574 |
| METTL1 | QTRT1 | A0A2Y9MZR9 | A0A2Y9LWZ0 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] | 0.437 |
| METTL1 | QTRT2 | A0A2Y9MZR9 | A0A2Y9LPB2 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. | 0.459 |
| METTL1 | TRUB1 | A0A2Y9MZR9 | A0A2Y9N592 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | Probable tRNA pseudouridine synthase 1 isoform X1. | 0.775 |
| METTL1 | TRUB2 | A0A2Y9MZR9 | A0A2Y9NSU5 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | Probable tRNA pseudouridine synthase 2 isoform X1. | 0.666 |
| METTL1 | YRDC | A0A2Y9MZR9 | A0A2Y9NHV5 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | yrdC domain-containing protein, mitochondrial. | 0.806 |
| METTL2A | PUS3 | A0A2Y9PNB6 | A0A2Y9LT95 | Methyltransferase-like protein 2A isoform X1. | tRNA pseudouridine(38/39) synthase. | 0.616 |
| METTL2A | QTRT2 | A0A2Y9PNB6 | A0A2Y9LPB2 | Methyltransferase-like protein 2A isoform X1. | Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. | 0.526 |
| METTL2A | THUMPD2 | A0A2Y9PNB6 | A0A2Y9N4S6 | Methyltransferase-like protein 2A isoform X1. | THUMP domain-containing protein 2 isoform X1. | 0.450 |
| METTL2A | YRDC | A0A2Y9PNB6 | A0A2Y9NHV5 | Methyltransferase-like protein 2A isoform X1. | yrdC domain-containing protein, mitochondrial. | 0.520 |
| PTS | QTRT1 | A0A2Y9M710 | A0A2Y9LWZ0 | 6-pyruvoyl tetrahydrobiopterin synthase. | Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] | 0.478 |
| PTS | QTRT2 | A0A2Y9M710 | A0A2Y9LPB2 | 6-pyruvoyl tetrahydrobiopterin synthase. | Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. | 0.478 |
| PUS3 | DKC1 | A0A2Y9LT95 | A0A2Y9MLZ2 | tRNA pseudouridine(38/39) synthase. | H/ACA ribonucleoprotein complex subunit 4. | 0.612 |
| PUS3 | METTL1 | A0A2Y9LT95 | A0A2Y9MZR9 | tRNA pseudouridine(38/39) synthase. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | 0.574 |