Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IZUMO3Izumo sperm-egg fusion protein 3. (218 aa)    
Predicted Functional Partners:
IZUMO1
Izumo sperm-egg fusion protein 1 isoform X1.
      
 0.735
IZUMO2
Izumo sperm-egg fusion protein 2.
   
  
 0.708
ACRV1
Acrosomal protein SP-10 isoform X1.
   
  
 0.650
IZUMO4
Izumo sperm-egg fusion protein 4 isoform X1.
      
 0.641
SPATA46
Spermatogenesis-associated protein 46 isoform X1.
   
  
 0.624
ACTRT2
Actin-related protein T2; Belongs to the actin family.
   
  
 0.541
ACR
Acrosin; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome.
     
  0.508
SLC35B3
Adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X1.
      
 0.484
TMEM239
Transmembrane protein 239 isoform X2.
  
    0.472
ISOC2
Isochorismatase domain-containing protein 2.
      
 0.448
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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