close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CEBPECCAAT/enhancer-binding protein. (281 aa)    
Predicted Functional Partners:
CDK4
Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.
   
 0.717
CDK2
Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily.
   
 0.713
DDIT3
DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]
  
 
 
 0.687
GFI1
Zinc finger protein Gfi-1 isoform X1.
    
 0.651
ATF4
Cyclic AMP-dependent transcription factor ATF-4 isoform X1.
   
 0.631
IRF8
Interferon regulatory factor 8 isoform X1.
    
 
 0.617
LOC111177826
Cytochrome c oxidase subunit 5A, mitochondrial isoform X1.
   
 0.615
TRIB1
Tribbles homolog 1.
   
 0.607
GFI1B
Zinc finger protein Gfi-1b isoform X2.
    
 0.594
CDKN1A
Cyclin-dependent kinase inhibitor 1.
   
 0.584
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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