TIRAP protein (Delphinapterus leucas) - STRING interaction network

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Score

TIRAP

Toll/interleukin-1 receptor domain-containing adapter protein. (226 aa)

Predicted Functional Partners:

TLR4

0.993

MYD88

0.992

TLR2

0.980

TRAF6

0.979

IRAK4

0.972

TLR9

0.971

TLR6

0.968

IRAK1

0.967

LY96

0.962

FADD

0.920

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FADD	IRAK1	A0A2Y9PNL8	A0A2Y9MHJ9	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Interleukin-1 receptor-associated kinase 1.	0.410
FADD	LY96	A0A2Y9PNL8	A0A2Y9PZM1	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Lymphocyte antigen 96.	0.459
FADD	MYD88	A0A2Y9PNL8	A0A2Y9LJK0	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.962
FADD	TIRAP	A0A2Y9PNL8	A0A2Y9LQB7	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Toll/interleukin-1 receptor domain-containing adapter protein.	0.920
FADD	TLR4	A0A2Y9PNL8	A0A2Y9NKP1	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Toll-like receptor 4 isoform X1; Belongs to the Toll-like receptor family.	0.666
FADD	TRAF6	A0A2Y9PNL8	A0A2Y9PAB2	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.701
IRAK1	FADD	A0A2Y9MHJ9	A0A2Y9PNL8	Interleukin-1 receptor-associated kinase 1.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.410
IRAK1	IRAK4	A0A2Y9MHJ9	A0A2Y9N4T5	Interleukin-1 receptor-associated kinase 1.	Interleukin-1 receptor-associated kinase 4 isoform X1.	0.999
IRAK1	LY96	A0A2Y9MHJ9	A0A2Y9PZM1	Interleukin-1 receptor-associated kinase 1.	Lymphocyte antigen 96.	0.728
IRAK1	MYD88	A0A2Y9MHJ9	A0A2Y9LJK0	Interleukin-1 receptor-associated kinase 1.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.999
IRAK1	TIRAP	A0A2Y9MHJ9	A0A2Y9LQB7	Interleukin-1 receptor-associated kinase 1.	Toll/interleukin-1 receptor domain-containing adapter protein.	0.967
IRAK1	TLR2	A0A2Y9MHJ9	A0A2Y9QIX5	Interleukin-1 receptor-associated kinase 1.	Toll-like receptor 2; Belongs to the Toll-like receptor family.	0.644
IRAK1	TLR4	A0A2Y9MHJ9	A0A2Y9NKP1	Interleukin-1 receptor-associated kinase 1.	Toll-like receptor 4 isoform X1; Belongs to the Toll-like receptor family.	0.834
IRAK1	TLR6	A0A2Y9MHJ9	A0A2Y9MRR6	Interleukin-1 receptor-associated kinase 1.	Toll-like receptor 6; Belongs to the Toll-like receptor family.	0.755
IRAK1	TLR9	A0A2Y9MHJ9	A0A2Y9N6G5	Interleukin-1 receptor-associated kinase 1.	LOW QUALITY PROTEIN: toll-like receptor 9.	0.593
IRAK1	TRAF6	A0A2Y9MHJ9	A0A2Y9PAB2	Interleukin-1 receptor-associated kinase 1.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.999
IRAK4	IRAK1	A0A2Y9N4T5	A0A2Y9MHJ9	Interleukin-1 receptor-associated kinase 4 isoform X1.	Interleukin-1 receptor-associated kinase 1.	0.999
IRAK4	LY96	A0A2Y9N4T5	A0A2Y9PZM1	Interleukin-1 receptor-associated kinase 4 isoform X1.	Lymphocyte antigen 96.	0.552
IRAK4	MYD88	A0A2Y9N4T5	A0A2Y9LJK0	Interleukin-1 receptor-associated kinase 4 isoform X1.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.999
IRAK4	TIRAP	A0A2Y9N4T5	A0A2Y9LQB7	Interleukin-1 receptor-associated kinase 4 isoform X1.	Toll/interleukin-1 receptor domain-containing adapter protein.	0.972