Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ANGPTL1Angiopoietin-related protein 1. (491 aa)    
Predicted Functional Partners:
ANGPTL8
Angiopoietin-like protein 8 isoform X1.
    
 0.706
TEK
Angiopoietin-1 receptor.
   
 0.653
ATG7
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]
    
 0.533
IGDCC4
Immunoglobulin superfamily DCC subclass member 4 isoform X1.
      
 0.516
TIE1
Tyrosine-protein kinase receptor Tie-1 isoform X1.
   
 0.511
KANSL2
KAT8 regulatory NSL complex subunit 2 isoform X1.
    
 0.481
MCRS1
Microspherule protein 1 isoform X1.
    
 0.440
GPIHBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1.
   
 
 0.435
VASH1
Vasohibin-1 isoform X1.
      
 0.430
MFAP5
Microfibrillar-associated protein 5 isoform X1.
   
 
 0.409
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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