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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ROCK2Rho-associated protein kinase 2 isoform X2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1416 aa)    
Predicted Functional Partners:
RHOA
Transforming protein RhoA.
   
 0.996
ROCK1
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
  
0.992
MYL2
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform.
    
 0.947
CTNNB1
Catenin beta-1.
    
 0.945
PPP1R12A
Protein phosphatase 1 regulatory subunit.
   
 0.937
LOC111162707
LIM domain kinase 2 isoform X1.
   
0.936
PPP1R12B
Protein phosphatase 1 regulatory subunit.
   
 0.936
LIMK1
LIM domain kinase 1 isoform X1.
   
0.934
PPP1R12C
Protein phosphatase 1 regulatory subunit.
   
 0.932
MYL12B
Myosin regulatory light chain 12B.
    
 0.931
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.