Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ROCK2Rho-associated protein kinase 2 isoform X2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1416 aa)    
Predicted Functional Partners:
ROCK1
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
  
0.999
RHOA
Transforming protein RhoA.
   
 0.987
PPP1R12B
Protein phosphatase 1 regulatory subunit.
   
 0.963
PPP1R12A
Protein phosphatase 1 regulatory subunit.
   
 0.963
LIMK1
LIM domain kinase 1 isoform X1.
    
0.958
PPP1R12C
Protein phosphatase 1 regulatory subunit.
   
 0.956
LOC111162707
LIM domain kinase 2 isoform X1.
    
0.954
CTNNB1
Catenin beta-1.
    
 0.949
MYL12B
Myosin regulatory light chain 12B.
    
 0.941
MYL9
Myosin regulatory light polypeptide 9.
    
 0.941
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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