close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)    
Predicted Functional Partners:
GNA14
Guanine nucleotide-binding protein subunit alpha-14.
    
 0.984
GNA11
Guanine nucleotide-binding protein subunit alpha-11.
    
 0.983
GNAQ
Guanine nucleotide-binding protein G(Q) subunit alpha isoform X1.
    
 0.976
LOC111176690
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X1.
     
 0.962
GNA15
Guanine nucleotide-binding protein subunit alpha-15 isoform X1.
    
 0.961
GNAI3
Guanine nucleotide-binding protein G(K) subunit alpha.
   
 0.961
GNAO1
Guanine nucleotide-binding protein G(O) subunit alpha isoform X1.
   
 0.960
ITPR2
Inositol 1,4,5-trisphosphate receptor type 2 isoform X1.
   
 0.955
GNG13
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13.
     
 0.953
CASR
Extracellular calcium-sensing receptor isoform X1.
     
 0.950
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.