LOC111165942 protein (Delphinapterus leucas)

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Score

LOC111165942

Erythropoietin receptor; Receptor for erythropoietin. (509 aa)

Predicted Functional Partners:

JAK2

0.998

EPO

0.996

JAK3

0.970

LYN

0.955

JAK1

0.951

TYK2

0.904

TFR2

0.815

CSF2

0.794

Ob

0.794

THPO

0.793

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSF2	EPO	A0A2Y9PGP5	A0A2Y9PM33	Granulocyte-macrophage colony-stimulating factor.	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	0.573
CSF2	JAK1	A0A2Y9PGP5	A0A2Y9P436	Granulocyte-macrophage colony-stimulating factor.	Tyrosine-protein kinase.	0.600
CSF2	JAK2	A0A2Y9PGP5	A0A2Y9N3T7	Granulocyte-macrophage colony-stimulating factor.	Tyrosine-protein kinase.	0.758
CSF2	JAK3	A0A2Y9PGP5	A0A2Y9M4G7	Granulocyte-macrophage colony-stimulating factor.	Tyrosine-protein kinase.	0.483
CSF2	LOC111165942	A0A2Y9PGP5	A0A2Y9LSV2	Granulocyte-macrophage colony-stimulating factor.	Erythropoietin receptor; Receptor for erythropoietin.	0.794
CSF2	THPO	A0A2Y9PGP5	A0A2Y9N4B7	Granulocyte-macrophage colony-stimulating factor.	Thrombopoietin isoform X1.	0.542
CSF2	TYK2	A0A2Y9PGP5	A0A2Y9LU92	Granulocyte-macrophage colony-stimulating factor.	Tyrosine-protein kinase.	0.447
EPO	CSF2	A0A2Y9PM33	A0A2Y9PGP5	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	Granulocyte-macrophage colony-stimulating factor.	0.573
EPO	JAK1	A0A2Y9PM33	A0A2Y9P436	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	Tyrosine-protein kinase.	0.779
EPO	JAK2	A0A2Y9PM33	A0A2Y9N3T7	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	Tyrosine-protein kinase.	0.931
EPO	JAK3	A0A2Y9PM33	A0A2Y9M4G7	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	Tyrosine-protein kinase.	0.794
EPO	LOC111165942	A0A2Y9PM33	A0A2Y9LSV2	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	Erythropoietin receptor; Receptor for erythropoietin.	0.996
EPO	LYN	A0A2Y9PM33	A0A2Y9LZZ2	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	Tyrosine-protein kinase.	0.584
EPO	Ob	A0A2Y9PM33	G8DLG4	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	Leptin isoform X1.	0.941
EPO	THPO	A0A2Y9PM33	A0A2Y9N4B7	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	Thrombopoietin isoform X1.	0.964
JAK1	CSF2	A0A2Y9P436	A0A2Y9PGP5	Tyrosine-protein kinase.	Granulocyte-macrophage colony-stimulating factor.	0.600
JAK1	EPO	A0A2Y9P436	A0A2Y9PM33	Tyrosine-protein kinase.	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	0.779
JAK1	JAK2	A0A2Y9P436	A0A2Y9N3T7	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.995
JAK1	JAK3	A0A2Y9P436	A0A2Y9M4G7	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.995
JAK1	LOC111165942	A0A2Y9P436	A0A2Y9LSV2	Tyrosine-protein kinase.	Erythropoietin receptor; Receptor for erythropoietin.	0.951