close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ICAM3Intercellular adhesion molecule 3 isoform X1. (545 aa)    
Predicted Functional Partners:
ITGAL
Integrin alpha-L; Belongs to the integrin alpha chain family.
   
 0.993
ITGB2
Integrin beta.
   
 0.972
CD209
CD209 antigen.
   
 0.937
ICAM1
Intercellular adhesion molecule 1.
  
  
0.920
ICAM2
Intercellular adhesion molecule 2 isoform X1.
   
 
0.919
CD4
T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]
      
 0.611
LOC111171171
Integrin alpha-M-like.
   
 0.548
LOC111182106
Integrin alpha-X-like isoform X1; Belongs to the integrin alpha chain family.
   
 0.548
ITGAM
Integrin alpha-M; Belongs to the integrin alpha chain family.
   
 0.548
ITGAE
Integrin alpha-E; Belongs to the integrin alpha chain family.
   
 0.548
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
Server load: medium (52%) [HD]