WRB protein (Delphinapterus leucas) - STRING interaction network

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Score

WRB

Tail-anchored protein insertion receptor WRB isoform X1. (183 aa)

Predicted Functional Partners:

ASNA1

0.982

CAMLG

0.940

SETD4

0.614

TBATA

0.608

DOPEY2

0.606

SEC61B

0.604

SGTA

0.596

UBL4A

0.565

LOC111163800

0.551

TMEM208

0.548

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASNA1	CAMLG	A0A2Y9M9D3	A0A2Y9PGZ1	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	Calcium signal-modulating cyclophilin ligand isoform X1.	0.935
ASNA1	SEC61B	A0A2Y9M9D3	A0A2Y9QKU1	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.674
ASNA1	SGTA	A0A2Y9M9D3	A0A2Y9MW18	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	Small glutamine-rich tetratricopeptide repeat-containing protein alpha.	0.796
ASNA1	TMEM208	A0A2Y9M9D3	A0A2Y9NW19	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	Transmembrane protein 208 isoform X1.	0.489
ASNA1	UBL4A	A0A2Y9M9D3	A0A2Y9MN00	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	Ubiquitin-like protein 4A isoform X1.	0.682
ASNA1	WRB	A0A2Y9M9D3	A0A2Y9LT94	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	Tail-anchored protein insertion receptor WRB isoform X1.	0.982
CAMLG	ASNA1	A0A2Y9PGZ1	A0A2Y9M9D3	Calcium signal-modulating cyclophilin ligand isoform X1.	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	0.935
CAMLG	SGTA	A0A2Y9PGZ1	A0A2Y9MW18	Calcium signal-modulating cyclophilin ligand isoform X1.	Small glutamine-rich tetratricopeptide repeat-containing protein alpha.	0.717
CAMLG	TMEM208	A0A2Y9PGZ1	A0A2Y9NW19	Calcium signal-modulating cyclophilin ligand isoform X1.	Transmembrane protein 208 isoform X1.	0.465
CAMLG	UBL4A	A0A2Y9PGZ1	A0A2Y9MN00	Calcium signal-modulating cyclophilin ligand isoform X1.	Ubiquitin-like protein 4A isoform X1.	0.488
CAMLG	WRB	A0A2Y9PGZ1	A0A2Y9LT94	Calcium signal-modulating cyclophilin ligand isoform X1.	Tail-anchored protein insertion receptor WRB isoform X1.	0.940
DOPEY2	TBATA	A0A2Y9LGR9	A0A2Y9PU59	Protein dopey-2 isoform X1.	Protein TBATA.	0.623
DOPEY2	WRB	A0A2Y9LGR9	A0A2Y9LT94	Protein dopey-2 isoform X1.	Tail-anchored protein insertion receptor WRB isoform X1.	0.606
LOC111163800	WRB	A0A2Y9LIF3	A0A2Y9LT94	SH3 domain-binding glutamic acid-rich protein-like isoform X1.	Tail-anchored protein insertion receptor WRB isoform X1.	0.551
SEC61B	ASNA1	A0A2Y9QKU1	A0A2Y9M9D3	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	0.674
SEC61B	SGTA	A0A2Y9QKU1	A0A2Y9MW18	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	Small glutamine-rich tetratricopeptide repeat-containing protein alpha.	0.693
SEC61B	UBL4A	A0A2Y9QKU1	A0A2Y9MN00	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	Ubiquitin-like protein 4A isoform X1.	0.520
SEC61B	WRB	A0A2Y9QKU1	A0A2Y9LT94	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	Tail-anchored protein insertion receptor WRB isoform X1.	0.604
SETD4	WRB	A0A2Y9LIC4	A0A2Y9LT94	SET domain-containing protein 4.	Tail-anchored protein insertion receptor WRB isoform X1.	0.614
SGTA	ASNA1	A0A2Y9MW18	A0A2Y9M9D3	Small glutamine-rich tetratricopeptide repeat-containing protein alpha.	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	0.796